T helper cells in synovial fluid of patients with rheumatoid arthritis primarily have a Th1 and a CXCR3+Th2 phenotype

T helper cells in synovial fluid of patients with rheumatoid arthritis primarily have a Th1 and a CXCR3+Th2 phenotype

Abstract Background The majority of CD4+ T helper (Th) cells found in the synovial fluid (SF) of patients with rheumatoid arthritis (RA) express CXCR3, a receptor associated with Th1 cells. In blood, subsets of Th2 and Th17 cells also express CXCR3, but it is unknown if these cells are present in RA...

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Bibliographic Details
Main Authors: Jonathan Aldridge, Anna-Karin H. Ekwall, Linda Mark, Beatrice Bergström, Kerstin Andersson, Inger Gjertsson, Anna-Carin Lundell, Anna Rudin
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Th1
Th2
TPh
TFh
Fibroblast-like synoviocytes
Online Access:http://link.springer.com/article/10.1186/s13075-020-02349-y

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http://link.springer.com/article/10.1186/s13075-020-02349-y

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