GITRL on dendritic cells aggravates house dust mite-induced airway inflammation and airway hyperresponsiveness by modulating CD4+ T cell differentiation

GITRL on dendritic cells aggravates house dust mite-induced airway inflammation and airway hyperresponsiveness by modulating CD4+ T cell differentiation

Abstract Background Glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) plays an important role in tumors, autoimmunity and inflammation. However, GITRL is not known to modulate the pathogenesis of allergic asthma. In this study, we investigated whether regula...

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Bibliographic Details
Main Authors: Yaping Wang, Kou Liao, Bo Liu, Chao Niu, Wenjing Zou, Lili Yang, Ting Wang, Daiyin Tian, Zhengxiu Luo, Jihong Dai, Qubei Li, Enmei Liu, Caihui Gong, Zhou Fu, Ying Li, Fengxia Ding
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Respiratory Research
Subjects:
GITRL
Dendritic cells
Asthma
Th1/Th2
Th17/Treg
Online Access:https://doi.org/10.1186/s12931-020-01583-x

Internet

https://doi.org/10.1186/s12931-020-01583-x

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