Elucidating the Pivotal Immunomodulatory and Anti-Inflammatory Potentials of Chloroquine and Hydroxychloroquine

Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of 4-aminoquinoline compounds with over 60 years of safe clinical usage. CQ and HCQ are able to inhibit the production of cytokines such as interleukin- (IL-) 1, IL-2, IL-6, IL-17, and IL-22. Also, CQ and HCQ inhibit the production of int...

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Bibliographic Details
Main Authors: Seidu A. Richard, Sylvanus Kampo, Maite Esquijarosa Hechavarria, Marian Sackey, Alexis D. B. Buunaaim, Eugene Dogkotenge Kuugbee, Thomas Winsum Anabah
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2020/4582612