Host proteome linked to HPV E7-mediated specific gene hypermethylation in cancer pathways
Abstract Background Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the target...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | Infectious Agents and Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13027-020-0271-4 |