Host proteome linked to HPV E7-mediated specific gene hypermethylation in cancer pathways

Abstract Background Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the target...

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Bibliographic Details
Main Authors: Nopphamon Na Rangsee, Pattamawadee Yanatatsaneejit, Trairak Pisitkun, Poorichaya Somparn, Pornrutsami Jintaridth, Supachai Topanurak
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Infectious Agents and Cancer
Subjects:
Online Access:https://doi.org/10.1186/s13027-020-0271-4