RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response. [version 1; referees: 2 approved]
Background: Hypoxia-inducible factor (HIF) transcription factors are well known to control the transcriptional response to hypoxia. Given the importance of cellular response to hypoxia, a number of pharmacological agents to interfere with this pathway have been developed and entered pre-clinical or...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2019-01-01
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Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/4-17/v1 |