RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response. [version 1; referees: 2 approved]

Background: Hypoxia-inducible factor (HIF) transcription factors are well known to control the transcriptional response to hypoxia. Given the importance of cellular response to hypoxia, a number of pharmacological agents to interfere with this pathway have been developed and entered pre-clinical or...

Full description

Bibliographic Details
Main Authors: Julianty Frost, Alessio Ciulli, Sonia Rocha
Format: Article
Language:English
Published: Wellcome 2019-01-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-17/v1