Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute <i>Campylobacter jejuni</i>-induced Enterocolitis in Mice

Pituitary Adenylate Cyclase-Activating Polypeptide Alleviates Intestinal, Extra-Intestinal and Systemic Inflammatory Responses during Acute <i>Campylobacter jejuni</i>-induced Enterocolitis in Mice

Human <i>Campylobacter jejuni</i> infections are emerging, and constitute a significant health burden worldwide. The ubiquitously expressed pituitary adenylate cyclase-activating polypeptide (PACAP) is well-known for its cell-protective and immunomodulatory effects. In our actual interve...

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Bibliographic Details
Main Authors: Markus M. Heimesaat, Soraya Mousavi, Sigri Kløve, Claudia Genger, Dennis Weschka, Andrea Tamas, Dora Reglodi, Stefan Bereswill
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pathogens
Subjects:
pituitary adenylate cyclase-activating polypeptide (PACAP)
cellular protection
anti-apoptotic properties
immune modulation
anti-inflammatory effects
cell proliferation and regeneration
Online Access:https://www.mdpi.com/2076-0817/9/10/805

Internet

https://www.mdpi.com/2076-0817/9/10/805

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