Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress

Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress

When cellular reducing enzymes fail to shield the cell from increased amounts of reactive oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and proteins are damaged and cellular transcription networks are activated. This condition can lead to the initiation and/or to...

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Bibliographic Details
Main Authors: Elisabeth Deindl, Judith-Irina Pagel
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:International Journal of Molecular Sciences
Subjects:
Egr-1
oxidative stress
atherosclerosis
NADPH oxidase inhibitor
pulmonary hypertension
signal transduction
MEK/ERK pathway
PKC
Online Access:http://www.mdpi.com/1422-0067/13/10/13104

Internet

http://www.mdpi.com/1422-0067/13/10/13104

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