Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos.

Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos.

Early-cleaving embryos are known to have better capacity to reach the blastocyst stage and produce better quality embryos compared to late-cleaving embryos. To investigate the significance of endoplasmic reticulum (ER) stress on early embryo cleavage kinetics and development, porcine embryos produce...

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Bibliographic Details
Main Authors: Naomi Dicks, Rodrigo C Bohrer, Karina Gutierrez, Marek Michalak, Luis B Agellon, Vilceu Bordignon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5669469?pdf=render

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http://europepmc.org/articles/PMC5669469?pdf=render

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