Hepatitis C virus NS4B protein induces epithelial-mesenchymal transition by upregulation of Snail

Hepatitis C virus NS4B protein induces epithelial-mesenchymal transition by upregulation of Snail

Abstract Background Chronic hepatitis C virus (HCV) infection is an important cause of hepatocellular carcinoma (HCC). Epithelial to mesenchymal transition (EMT) is a key process associated with tumor metastasis and poor prognosis. HCV infection, HCV core and NS5A protein could induce EMT process, b...

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Bibliographic Details
Main Authors: Bicheng Hu, Shenggao Xie, Yuqian Hu, Wen Chen, Xiaofan Chen, Yi Zheng, Xinxing Wu
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Virology Journal
Subjects:
HCV
Epithelial to mesenchymal (EMT)
Cadherin
Snail
Hippo pathway
Online Access:http://link.springer.com/article/10.1186/s12985-017-0737-1

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http://link.springer.com/article/10.1186/s12985-017-0737-1

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