Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

<p>Abstract</p> <p>Background</p> <p>Pancreatic cancer retains a poor prognosis among the gastrointestinal cancers. It affects 230,000 individuals worldwide, has a very high mortality rate, and remains one of the most challenging malignancies to treat successfully. Trea...

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Bibliographic Details
Main Authors: Azorsa David O, Gonzales Irma M, Basu Gargi D, Choudhary Ashish, Arora Shilpi, Bisanz Kristen M, Kiefer Jeffrey A, Henderson Meredith C, Trent Jeffrey M, Von Hoff Daniel D, Mousses Spyro
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/7/1/43

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http://www.translational-medicine.com/content/7/1/43

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