Hypoxia-Induced TPM2 Methylation is Associated with Chemoresistance and Poor Prognosis in Breast Cancer

Hypoxia-Induced TPM2 Methylation is Associated with Chemoresistance and Poor Prognosis in Breast Cancer

Background/Aims: Tropomyosin-2 (TPM2) plays important roles in functions of the cytoskeleton, such as cytokinesis, vesicle transport, cell proliferation, migration and apoptosis,and these functions imply that TPM2 also plays a role in cancer development. Indeed, it has been shown that TPM2 plays a c...

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Bibliographic Details
Main Authors: Jinfeng Zhang, Jian Zhang, Shouping Xu, Xianyu Zhang, Peiyuan Wang, Hao Wu, Bingshu Xia, Guangwen Zhang, Bo Lei, Lin Wan, Dekai Zhang, Da Pang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Tpm2
Hypoxia
Methylation
Breast cancer
Paclitaxel
Online Access:https://www.karger.com/Article/FullText/487162

Internet

https://www.karger.com/Article/FullText/487162

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