Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

Abstract Novel targets to arrest neurodegeneration in several dementing conditions involving misfolded protein accumulations may be found in the diverse signaling pathways of the Mammalian/mechanistic target of rapamycin (mTOR). As a nutrient sensor, mTOR has important homeostatic functions to regul...

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Bibliographic Details
Main Authors: Henry Querfurth, Han-Kyu Lee
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Neurodegeneration
Subjects:
Alzheimer’s
mTOR
Rapamycin
Insulin signaling
Akt
Parkinson’s
Online Access:https://doi.org/10.1186/s13024-021-00428-5

Internet

https://doi.org/10.1186/s13024-021-00428-5

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