Carbamazepine protects against megencephaly and abnormal expression of BDNF and Nogo signaling components in the mceph/mceph mouse

Carbamazepine protects against megencephaly and abnormal expression of BDNF and Nogo signaling components in the mceph/mceph mouse

Carbamazepine (CBZ) is a commonly used antiepileptic drug known to block voltage-gated sodium channels. Infants exposed to CBZ in utero show reduced head circumference, for reasons unknown. We investigated CBZ's effect on neural growth in megencephaly (mceph/mceph) mice lacking functional Kv1.1...

Full description

Bibliographic Details
Main Authors: Catharina Lavebratt, Alexandra Trifunovski, Ann-Sophie Persson, Fu-Hua Wang, Tomas Klason, Inger Öhman, Anna Josephsson, Lars Olson, Christian Spenger, Martin Schalling
Format: Article
Language:English
Published: Elsevier 2006-11-01
Series:Neurobiology of Disease
Subjects:
Megalencephaly
Epilepsy
Antiepileptic drug, potassium channel
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106001756

Internet

http://www.sciencedirect.com/science/article/pii/S0969996106001756

Similar Items