Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause

In a perimenopausal model of middle aged rats, the astrocyte estrogen receptor-alpha (ERa): ER-beta (ERb) ratio increased with the onset of acyclicity (constant estrus, CE) in association with impaired neurotrophic responses to estradiol (E2). We report additional data on irregular cycling (IR) from...

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Bibliographic Details
Main Authors: Caleb E Finch, T E Morgan
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00179/full