Invariant natural killer T cell agonist modulates experimental focal and segmental glomerulosclerosis.

Invariant natural killer T cell agonist modulates experimental focal and segmental glomerulosclerosis.

A growing body of evidence demonstrates a correlation between Th2 cytokines and the development of focal and segmental glomerulosclerosis (FSGS). Therefore, we hypothesized that GSL-1, a monoglycosylceramide from Sphingomonas ssp. with pro-Th1 activity on invariant Natural Killer T (iNKT) lymphocyte...

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Bibliographic Details
Main Authors: Rafael L Pereira, Vanessa O Reis, Patricia Semedo, Bruna N Buscariollo, Cassiano Donizetti-Oliveira, Marcos A Cenedeze, Maria Fernanda Soares, Alvaro Pacheco-Silva, Paul B Savage, Niels O S Câmara, Alexandre C Keller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3299669?pdf=render

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http://europepmc.org/articles/PMC3299669?pdf=render

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