The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue

The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue

Abstract Background It is well known that androgen-deprivation therapy (ADT) can inevitably drive prostate cancer (PCa) cells into a castration-resistant state. According to the “Warburg effect”, the metabolism of aggressive tumor cells increases significantly. The growth of cancer cells depends on...

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Bibliographic Details
Main Authors: Ximing Li, Zhi Chen, Zuan Li, Guihai Huang, Junhao Lin, Qiang Wei, Jianbo Liang, Wei Li
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Urology
Subjects:
Prostate cancer
PFKFB4
CRPC
LNCaP cells
Metabolism
Online Access:http://link.springer.com/article/10.1186/s12894-020-00635-0

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http://link.springer.com/article/10.1186/s12894-020-00635-0

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