Functional changes in pulmonary arterial endothelial cells associated with BMPR2 mutations.

Functional changes in pulmonary arterial endothelial cells associated with BMPR2 mutations.

Pulmonary arterial hypertension (PAH) is a devastating disease characterized by abnormal remodeling of small, peripheral pulmonary arteries. Germline mutations in the bone morphogenetic protein receptor type 2 (BMPR2) gene are a major risk factor for developing PAH. At present, the correlation betwe...

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Bibliographic Details
Main Authors: Hu Wang, Ruirui Ji, Jie Meng, Qiqiong Cui, Wenxin Zou, Lei Li, Guoliang Wang, Li Sun, Zhaohui Li, Lei Huo, Yuxin Fan, Daniel J Penny
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4154762?pdf=render

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http://europepmc.org/articles/PMC4154762?pdf=render

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