Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER

Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER

EpiTYPER® is a mass spectrometry-based bisulfite sequencing method that enables region-specific DNA methylation analysis in a quantitative and high-throughput fashion. The technology targets genomic regions of 100-600 base pairs and results in the quantitative measurement of DNA methylation levels l...

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Bibliographic Details
Main Authors: H. Eka D. Suchiman, Roderick C. Slieker, Dennis eKremer, P. Eline eSlagboom, Bastiaan T Heijmans, Elmar Wouter Tobi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Genetics
Subjects:
DNA Methylation
Mass Spectrometry
Quality control
MALDI-TOF MS
protocol
Data handling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00287/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00287/full

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