Collagen-dependent platelet dysfunction and its relevance to either mitochondrial ROS or cytosolic superoxide generation: a question about the quality and functional competence of long-stored platelets

Collagen-dependent platelet dysfunction and its relevance to either mitochondrial ROS or cytosolic superoxide generation: a question about the quality and functional competence of long-stored platelets

Abstract Background Upon vascular damage, the exposed subendothelial matrix recruits circulating platelets to site of injury while inducing their firm adhesion mainly via GPVI-collagen interaction. GPVI also supports aggregatory and pro-coagulant functions in arterial shear rate even on the matrix o...

Full description

Bibliographic Details
Main Authors: Ehteramolsadat Hosseini, Saba Hojjati, Safoora Afzalniaye gashti, Mehran Ghasemzadeh
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Thrombosis Journal
Subjects:
Adhesion
Aggregation
Collagen
Platelet
Reactive oxygen species
Spreading
Online Access:http://link.springer.com/article/10.1186/s12959-020-00233-y

Internet

http://link.springer.com/article/10.1186/s12959-020-00233-y

Similar Items