c-Myc activates <it>BRCA1 </it>gene expression through distal promoter elements in breast cancer cells

<p>Abstract</p> <p>Background</p> <p>The <it>BRCA1 </it>gene plays an important role in the maintenance of genomic stability. BRCA1 inactivation contributes to breast cancer tumorigenesis. An increasing number of transcription factors have been shown to regu...

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Bibliographic Details
Main Authors: Huo Dezheng, Collins Cindy, Borowicz Stanley, Xu Jinhua, Chen Yinghua, Olopade Olufunmilayo I
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/246