Practical considerations for choosing a mouse model of Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is behaviorally identified by progressive memory impairment and pathologically characterized by the triad of β-amyloid plaques, neurofibrillary tangles, and neurodegeneration. Genetic mutations and risk factors have been identified that are either causal or modify t...

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Bibliographic Details
Main Authors: Joanna L. Jankowsky, Hui Zheng
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Molecular Neurodegeneration
Subjects:
APP
Online Access:http://link.springer.com/article/10.1186/s13024-017-0231-7