A Giant Right Heart Thrombus-in-Transit: The Challenge of Anticoagulation in Factor V Leiden Thrombophilia

Factor V Leiden (FVL) is an autosomal dominant condition resulting in thrombophilia. Factor V normally acts as a cofactor for prothrombinase, helping cleave prothrombin to thrombin. A single point mutation in it disrupts factor V, making it unreceptive to protein C and increasing the risk of thrombo...

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Bibliographic Details
Main Authors: Andrew Chu, Thu Thu Aung, Minni Shreya Arumugam, Mauricio Danckers, Mohi Mitiek, Jonathan Leslie
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2018/9098604