Metabolic Changes Associated with a Rat Model of Diabetic Depression Detected by Ex Vivo 1H Nuclear Magnetic Resonance Spectroscopy in the Prefrontal Cortex, Hippocampus, and Hypothalamus

Diabetic patients often present with comorbid depression. However, the pathogenetic mechanisms underlying diabetic depression (DD) remain unclear. To explore the mechanisms underpinning the pathogenesis of the disease, we used ex vivo 1H nuclear magnetic resonance spectroscopy and immunohistochemist...

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Bibliographic Details
Main Authors: Kun Liu, Liangcai Zhao, Wen Xu, Qiuting Lin, Yongjin Zhou, Xiaoyan Huang, Xinjian Ye, Jiawei He, Guanghui Bai, Zhihan Yan, Hongchang Gao
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2018/6473728