Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients.

Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients.

BACKGROUND:Bronchiectasis is accompanied by chronic bronchial infection that may drive disease progression. However, the evidence base for antibiotic therapy is limited. DNA based methods offer better identification and quantification of microbial constituents of sputum than standard clinical cultur...

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Bibliographic Details
Main Authors: Michael J Cox, Elena M Turek, Catherine Hennessy, Ghazala K Mirza, Phillip L James, Meg Coleman, Andrew Jones, Robert Wilson, Diana Bilton, William O C Cookson, Miriam F Moffatt, Michael R Loebinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5295668?pdf=render

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http://europepmc.org/articles/PMC5295668?pdf=render

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