Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies.

Involvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies.

Glomerular protein handling mechanisms have received much attention in studies of nephrotic syndrome. Histopathological findings in renal biopsies from severely proteinuric patients support the likelihood of protein endocytosis by podocytes. ClC-5 is involved in the endocytosis of albumin in the pro...

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Main Authors: Monica Ceol, Emilia Tiralongo, Hans J Baelde, Daniela Vianello, Giovanni Betto, Annunziata Marangelli, Luciana Bonfante, Marialuisa Valente, Mila Della Barbera, Angela D'Angelo, Franca Anglani, Dorella Del Prete
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3454393?pdf=render

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http://europepmc.org/articles/PMC3454393?pdf=render

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