Overexpression of PRDX4 Modulates Tumor Microenvironment and Promotes Urethane-Induced Lung Tumorigenesis

Peroxiredoxin 4 (PRDX4), initially reported as an antioxidant, is overexpressed in lung cancer and participates in its progression. However, its role in the urethane-induced lung tumor model is undetermined. The aim of this study was to investigate the effect of PRDX4 overexpression on carcinogen-in...

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Bibliographic Details
Main Authors: Jianbo Zheng, Xin Guo, Yuka Nakamura, Xiaolei Zhou, Reimon Yamaguchi, Jing Zhang, Yasuhito Ishigaki, Hidetaka Uramoto, Sohsuke Yamada
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/8262730