Examination of effects of GSK3β phosphorylation, β-catenin phosphorylation, and β-catenin degradation on kinetics of Wnt signaling pathway using computational method

<p>Abstract</p> <p>Background</p> <p>Recent experiments have explored effects of activities of kinases other than the well-studied GSK3β, in wnt pathway signaling, particularly at the level of β-catenin. It has also been found that the kinase PKA attenuates β-catenin de...

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Bibliographic Details
Main Author: Sun Ying-Chieh
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Theoretical Biology and Medical Modelling
Online Access:http://www.tbiomed.com/content/6/1/13