Nullomers: really a matter of natural selection?

Nullomers are short DNA sequences that are absent from the genomes of humans and other species. Assuming that nullomers are the signatures of natural selection against deleterious sequences in humans, the use of nullomers in drug target identification, pesticide development, environmental monitoring...

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Bibliographic Details
Main Authors: Claudia Acquisti, George Poste, David Curtiss, Sudhir Kumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1995752?pdf=render