NMDA receptors on parvalbumin-positive interneurons and pyramidal neurons both contribute to MK-801 induced gamma oscillatory disturbances: Complex relationships with behaviour

NMDA receptors on parvalbumin-positive interneurons and pyramidal neurons both contribute to MK-801 induced gamma oscillatory disturbances: Complex relationships with behaviour

Background: NMDAr antagonists induce disturbances to gamma frequency oscillations, including increasing ongoing gamma activity and reducing evoked gamma oscillations. We sought to investigate the role parvalbumin (PV+) neurons and CaMKIIα+ pyramidal cells in NMDAr antagonist-induced disturbances in...

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Bibliographic Details
Main Authors: Matthew R. Hudson, Elysia Sokolenko, Terence J. O'Brien, Nigel C. Jones
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Subjects:
NMDA receptor antagonism
Behaviour
Electrophysiology
Gamma oscillations
Mice
Schizophrenia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119303006

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http://www.sciencedirect.com/science/article/pii/S0969996119303006

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