Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin

Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin

Both agonist studies and loss-of-function models indicate that PPARγ plays an important role in cutaneous biology. Since PPARγ has a high level of basal activity, we hypothesized that epidermal PPARγ would regulate normal homeostatic processes within the epidermis. In this current study, we performe...

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Bibliographic Details
Main Authors: Raymond L. Konger, Ethel Derr-Yellin, Teresa A. Zimmers, Terrence Katona, Xiaoling Xuei, Yunlong Liu, Hong-Ming Zhou, Ed Ronald Simpson, Matthew J. Turner
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
peroxisome proliferator-activated receptor gamma
transcriptomic changes
cutaneous phenotype
asebia
Online Access:https://www.mdpi.com/1422-0067/22/16/8634

Internet

https://www.mdpi.com/1422-0067/22/16/8634

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