Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures

Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures

Abstract Background There is increasing appreciation that non-cancer cells within the tumour microenvironment influence cancer progression and anti-cancer drug efficacy. For metastatic prostate cancer (PCa), the bone marrow microenvironment influences metastasis, drug response, and possibly drug res...

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Bibliographic Details
Main Authors: Eman Mosaad, Karen Chambers, Kathryn Futrega, Judith Clements, Michael Robert Doran
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Prostate cancer
Bone marrow stromal cells
Co-culture
Microwell-mesh platform
3D culture
Online Access:http://link.springer.com/article/10.1186/s12885-018-4473-8

Internet

http://link.springer.com/article/10.1186/s12885-018-4473-8

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