Temporal modulation of collective cell behavior controls vascular network topology

Temporal modulation of collective cell behavior controls vascular network topology

Vascular network density determines the amount of oxygen and nutrients delivered to host tissues, but how the vast diversity of densities is generated is unknown. Reiterations of endothelial-tip-cell selection, sprout extension and anastomosis are the basis for vascular network generation, a process...

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Bibliographic Details
Main Authors: Esther Kur, Jiha Kim, Aleksandra Tata, Cesar H Comin, Kyle I Harrington, Luciano da F Costa, Katie Bentley, Chenghua Gu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-02-01
Series:eLife
Subjects:
computational modeling
tip cell
temporal regulation
vascular topology
delta-notch
angiogensis
Online Access:https://elifesciences.org/articles/13212

Internet

https://elifesciences.org/articles/13212

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