Salvianolic Acid A Protects H9c2 Cells from Arsenic Trioxide-Induced Injury via Inhibition of the MAPK Signaling Pathway

Salvianolic Acid A Protects H9c2 Cells from Arsenic Trioxide-Induced Injury via Inhibition of the MAPK Signaling Pathway

Background/Aims: This study aimed to investigate whether Salvianolic acid A (Sal A) conferred cardiac protection against Arsenic trioxide (ATO)-induced cardiotoxicity in H9c2 cells by inhibiting MAPK pathways activation. Methods: H9c2 cardiac cells were exposed to 10 µM ATO for 24 h to induce cytoto...

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Bibliographic Details
Main Authors: Jing-yi Zhang, Gui-bo Sun, Yun Luo, Min Wang, Wei Wang, Yu-yang Du, Ying-li Yu, Xiao-bo Sun
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Arsenic trioxide
Salvianolic acid A
Cardiotoxicity
Apoptosis
Oxidative stress
MAPK
Online Access:http://www.karger.com/Article/FullText/472409

Internet

http://www.karger.com/Article/FullText/472409

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