Improved HIV-positive infant survival is correlated with high levels of HIV-specific ADCC activity in multiple cohorts

Improved HIV-positive infant survival is correlated with high levels of HIV-specific ADCC activity in multiple cohorts

Summary: Defining immune responses that protect humans against diverse HIV strains has been elusive. Studying correlates of protection from mother-to-child transmission provides a benchmark for HIV vaccine protection because passively transferred HIV antibodies are present during infant exposure to...

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Bibliographic Details
Main Authors: Zak A. Yaffe, Nicole E. Naiman, Jennifer Slyker, Bruce D. Wines, Barbra A. Richardson, P. Mark Hogarth, Rose Bosire, Carey Farquhar, Dorothy Mbori Ngacha, Ruth Nduati, Grace John-Stewart, Julie Overbaugh
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports Medicine
Subjects:
human immunodeficiency virus (HIV)
antibody-dependent cellular cytotoxicity (ADCC)
mother-to-child transmission (MTCT)
passive antibody transfer
maternal antibodies
pediatric HIV
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121000707

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http://www.sciencedirect.com/science/article/pii/S2666379121000707

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