Modeling Type 1 Diabetes Using Pluripotent Stem Cell Technology

Induced pluripotent stem cell (iPSC) technology is increasingly being used to create in vitro models of monogenic human disorders. This is possible because, by and large, the phenotypic consequences of such genetic variants are often confined to a specific and known cell type, and the genetic varian...

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Bibliographic Details
Main Authors: Kriti Joshi, Fergus Cameron, Swasti Tiwari, Stuart I. Mannering, Andrew G. Elefanty, Edouard G. Stanley
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.635662/full