Transplantation of GABAergic Cells Derived from Bioreactor-Expanded Human Neural Precursor Cells Restores Motor and Cognitive Behavioral Deficits in a Rodent Model of Huntington's Disease

Huntington's disease (HD) is a neurodegenerative disorder that is characterized by progressive dementia, choreiform involuntary movements, and emotional deterioration. Neuropathological features include the progressive degeneration of striatal γ-aminobutyric acid (GABA) neurons. New therapeutic...

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Bibliographic Details
Main Authors: Marcus C. McLeod, Nao R. Kobayashi, Arindom Sen, Behnam A. Baghbaderani, Damaso Sadi, Ruperto Ulalia, Leo A. Behie, Ivar Mendez M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2013-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X658809