Macromolecular crowding induces holo α-lactalbumin aggregation by converting to its apo form.

Macromolecular crowding has been shown to have an exacerbating effect on the aggregation propensity of amyloidogenic proteins; while having an inhibitory effect on the non-amyloidogenic proteins. However, the results concerning aggregation propensity of non-amyloidogenic proteins have not been convi...

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Bibliographic Details
Main Authors: Shruti Mittal, Laishram Rajendrakumar Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4250181?pdf=render