Metabolic Plasticity of Acute Myeloid Leukemia

Metabolic Plasticity of Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is one of the most common and life-threatening leukemias. A highly diverse and flexible metabolism contributes to the aggressiveness of the disease that is still difficult to treat. By using different sources of nutrients for energy and biomass supply, AML cells gain met...

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Bibliographic Details
Main Authors: Johanna Kreitz, Christine Schönfeld, Marcel Seibert, Verena Stolp, Islam Alshamleh, Thomas Oellerich, Björn Steffen, Harald Schwalbe, Frank Schnütgen, Nina Kurrle, Hubert Serve
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
acute myeloid leukemia
metabolic plasticity
aerobic glycolysis
TCA cycle
oxidative phosphorylation
amino acids
fatty acids
leukemic stem cells
drug resistance
redox homeostasis
Online Access:https://www.mdpi.com/2073-4409/8/8/805

Internet

https://www.mdpi.com/2073-4409/8/8/805

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