Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry.

Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry.

Unless repaired, DNA damage can drive mutagenesis or cell death. DNA repair proteins may therefore be used as biomarkers in disease etiology or therapeutic response prediction. Thus, the accurate determination of DNA repair protein expression and genotype is of fundamental importance. Among DNA repa...

Full description

Bibliographic Details
Main Authors: Güldal Kirkali, Pawel Jaruga, Prasad T Reddy, Alessandro Tona, Bryant C Nelson, Mengxia Li, David M Wilson, Miral Dizdaroglu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726725?pdf=render

Internet

http://europepmc.org/articles/PMC3726725?pdf=render

Similar Items