Antibiotic drugs targeting bacterial RNAs

RNAs have diverse structures that include bulges and internal loops able to form tertiary contacts or serve as ligand binding sites. The recent increase in structural and functional information related to RNAs has put them in the limelight as a drug target for small molecule therapy. In addition, th...

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Bibliographic Details
Main Authors: Weiling Hong, Jie Zeng, Jianping Xie
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
RNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383514000641