Ciliary beating recovery in deficient human airway epithelial cells after lentivirus ex vivo gene therapy.
Primary Ciliary Dyskinesia is a heterogeneous genetic disease that is characterized by cilia dysfunction of the epithelial cells lining the respiratory tracts, resulting in recurrent respiratory tract infections. Despite lifelong physiological therapy and antibiotics, the lungs of affected patients...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2650261?pdf=render |