The spectrum of BRCA1 gene mutations in early onset breast cancer patients from Russia

The spectrum of BRCA1 gene mutations in early onset breast cancer patients from Russia

Aim of the study. Aim of the study was to estimate the occurrence of pathogenic mutations in the BRCA1 gene in Russian breast cancer patients.Material and methods. Complete coding sequence of the BRCA1 gene of 445 early onset  breast cancer patients (under 40 years) from Novosibirsk region (Russia)...

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Bibliographic Details
Main Authors: M. S. Anisimenko, G. A. Paul, A. E. Kozyakov, N. I. Gutkina, D. A. Berdyugina, A. Yu. Garanin, A. V. Butorina, E. V. Gornostaeva, K. F. Khafizov, Yu. V. Vyatkin, D. N. Shtokalo, S. P. Kovalenko
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2018-09-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
brca1 gene
mutation
early onset breast cancer
hereditary cancer
ngs
targeted sequencing
Online Access:https://www.siboncoj.ru/jour/article/view/816

Internet

https://www.siboncoj.ru/jour/article/view/816

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