MicroRNA-29 impairs the early phase of reprogramming process by targeting active DNA demethylation enzymes and Wnt signaling

MicroRNA-29 impairs the early phase of reprogramming process by targeting active DNA demethylation enzymes and Wnt signaling

Somatic cell reprogramming by transcription factors and other modifiers such as microRNAs has opened broad avenues for the study of developmental processes, cell fate determination, and interplay of molecular mechanisms in signaling pathways. However, many of the mechanisms that drive nuclear reprog...

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Bibliographic Details
Main Authors: Mariane Serra Fráguas, Reto Eggenschwiler, Jeannine Hoepfner, Josiane Lilian dos Santos Schiavinato, Rodrigo Haddad, Lucila Habib Bourguignon Oliveira, Amélia Góes Araújo, Marco Antônio Zago, Rodrigo Alexandre Panepucci, Tobias Cantz
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Stem Cell Research
Subjects:
Cellular reprogramming
miR-29
WNT signaling
Ten-eleven translocated 1 (TET1) gene
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116302215

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http://www.sciencedirect.com/science/article/pii/S1873506116302215

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