White matter disease in midlife is heritable, related to hypertension, and shares some genetic influence with systolic blood pressure

White matter disease in the brain increases with age and cardiovascular disease, emerging in midlife, and these associations may be influenced by both genetic and environmental factors. We examined the frequency, distribution, and heritability of abnormal white matter and its association with hypert...

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Bibliographic Details
Main Authors: Christine Fennema-Notestine, PhD, Linda K. McEvoy, PhD, Randy Notestine, MS, Matthew S. Panizzon, PhD, Wai-Ying Wendy Yau, Carol E. Franz, PhD, Michael J. Lyons, PhD, Lisa T. Eyler, PhD, Michael C. Neale, PhD, Hong Xian, PhD, Ruth E. McKenzie, PhD, William S. Kremen, PhD
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:NeuroImage: Clinical
Subjects:
MRI
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158216301814