circCELSR1 facilitates ovarian cancer proliferation and metastasis by sponging miR-598 to activate BRD4 signals

Abstract Background Ovarian cancer is one of the most common gynecologic cancers and has high mortality rate due to the lack of early diagnosis method and efficient therapeutic agents. circCELSR1 is up-regulated in ovarian cancer, but its role and mechanisms in ovarian cancer are unclear. Methods Ge...

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Bibliographic Details
Main Authors: Xiang-Yang Zeng, Jing Yuan, Chen Wang, Da Zeng, Jia-Hui Yong, Xiao-Yan Jiang, Hua Lan, Song-Shu Xiao
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Molecular Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s10020-020-00194-y