Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

Collagen is a major component of the extracellular matrix and its integrity is essential for connective tissue and organ function. The importance of proteins involved in intracellular collagen post-translational modification, folding and transport was recently highlighted from studies on recessive f...

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Bibliographic Details
Main Authors: Melissa E Heard, Roberta Besio, MaryAnn Weis, Jyoti Rai, David M Hudson, Milena Dimori, Sarah M Zimmerman, Jeffrey A Kamykowski, William R Hogue, Frances L Swain, Marie S Burdine, Samuel G Mackintosh, Alan J Tackett, Larry J Suva, David R Eyre, Roy Morello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4847768?pdf=render

Internet

http://europepmc.org/articles/PMC4847768?pdf=render

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