The Oligosaccharide Galactose-α-1,3-Galactose and the α-Gal Syndrome: Insights from an Epitope that is Causal in Immunoglobulin E-Mediated Immediate and Delayed Anaphylaxis

The Oligosaccharide Galactose-α-1,3-Galactose and the α-Gal Syndrome: Insights from an Epitope that is Causal in Immunoglobulin E-Mediated Immediate and Delayed Anaphylaxis

Galactose-α-1,3-galactose (α-Gal) is an oligosaccharide that was first described as a cause of immunoglobulin E-mediated anaphylaxis in cases of first-in-man reactions to the monoclonal antibody cetuximab. Soon thereafter, immunoglobulin E antibodies to this epitope were linked with anaphylactic epi...

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Bibliographic Details
Main Authors: Jeffrey M. Wilson, Thomas A.E. Platts-Mills
Format: Article
Language:English
Published: European Medical Journal 2018-07-01
Series:European Medical Journal Allergy & Immunology
Subjects:
allergen
delayed anaphylaxis to red meat
food allergy
galactose-α-1
3-galactose (α-gal)
glycolipid
Online Access:https://www.emjreviews.com/allergy-immunology/article/the-oligosaccharide-galactose-%ce%b1-13-galactose-and-the-%ce%b1-gal-syndrome-insights-from-an-epitope-that-is-causal-in-immunoglobulin-e-mediated-immediate-and-delayed-anaphylaxis/

Internet

https://www.emjreviews.com/allergy-immunology/article/the-oligosaccharide-galactose-%ce%b1-13-galactose-and-the-%ce%b1-gal-syndrome-insights-from-an-epitope-that-is-causal-in-immunoglobulin-e-mediated-immediate-and-delayed-anaphylaxis/

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