Improved retroviral suicide gene transfer in colon cancer cell lines after cell synchronization with methotrexate

Improved retroviral suicide gene transfer in colon cancer cell lines after cell synchronization with methotrexate

<p>Abstract</p> <p>Background</p> <p>Cancer gene therapy by retroviral vectors is mainly limited by the level of transduction. Retroviral gene transfer requires target cell division. Cell synchronization, obtained by drugs inducing a reversible inhibition of DNA synthes...

Full description

Bibliographic Details
Main Authors: Nordlinger Bernard, Penna Christophe, Goere Diane, Noullet Severine, Capron Claude, Kraemer Aurore, Finzi Laetitia, Legagneux Josette, Emile Jean-Fançois, Malafosse Robert
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/92

Internet

http://www.jeccr.com/content/30/1/92

Similar Items