Delayed Influence of Spinal Cord Injury on the Amino Acids of NO• Metabolism in Rat Cerebral Cortex Is Attenuated by Thiamine

Delayed Influence of Spinal Cord Injury on the Amino Acids of NO• Metabolism in Rat Cerebral Cortex Is Attenuated by Thiamine

Severe spinal cord injuries (SCIs) result in chronic neuroinflammation in the brain, associated with the development of cognitive and behavioral impairments. Nitric oxide (NO•) is a gaseous messenger involved in neuronal signaling and inflammation, contributing to nitrosative stress under dysregulat...

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Bibliographic Details
Main Authors: Alexandra Boyko, Alexander Ksenofontov, Sergey Ryabov, Lyudmila Baratova, Anastasia Graf, Victoria Bunik
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Medicine
Subjects:
amino acids metabolism
cerebral cortex
nitric oxide precursors
glutathione
spinal cord injury
thiamine
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00249/full

Internet

http://journal.frontiersin.org/article/10.3389/fmed.2017.00249/full

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