Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis

Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force. Employing optical coherence tomography (OCT), we generated plaque...

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Bibliographic Details
Main Authors: Andrea Milzi, Enrico Domenico Lemma, Rosalia Dettori, Kathrin Burgmaier, Nikolaus Marx, Sebastian Reith, Mathias Burgmaier
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
optical coherence tomography
coronary artery disease
plaque vulnerability
plaque rupture
myocardial infarction
plaque biomechanics
Online Access:https://elifesciences.org/articles/64020

Internet

https://elifesciences.org/articles/64020

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